The markets were little changed on Tuesday, with the Nasdaq Composite edging lower after eking out another record high, as the Federal Reserve's meeting kicks off.
Pfizer Inc (PFE.N), the largest U.S. drugmaker, reported quarterly revenue that missed estimates as sales of its key drugs fell short of expectations.

The tax-free treatment of the spin-offs Dow Chemical Co and DuPont plan to carry out after they merge their businesses is a prime driv

U.S. stocks eked out small gains on Monday morning, helped by gains in materials and consumer stocks, as investors stayed cautious after last week's strong gains and ahead of Thanksgiving.
Pfizer Inc on Monday said it would buy Botox maker Allergan Plc in a record-breaking deal worth $160 billion, designed to cut the company's U.S. tax bill by moving its headquarters to Ireland.
Pfizer Inc., the largest U.S. drug maker, may soon redomicile in Ireland should it complete a massive acquisition of Dublin-based Allergan, the manufacturer of Botox.
The 500 largest American companies hold more than $2.1 trillion in accumulated profits offshore to avoid U.S. taxes and would collectively owe an estimated $620 billion in U.S. taxes if they repatriated the funds, according to a study released on Tuesday.
Foreign exchange swings really hurt North American businesses in late 2014.
Economic growth in the U.S. is slowing--our economy expanded at a slower pace than forecast in the fourth quarter. Data is clouding the picture.